|
|
L-glutamate + 7,8-dihydropteroate + ATP <=> H+ + 7,8-dihydrofolate + phosphate + ADP
|
6.3.2.12
dihydrofolate synthase
6.3.2.17
tetrahydrofolate synthase
|
–
–
|
BMK
|
| |
BRENDA:
BR104
KEGG:
R02237
MetaCyc:
DIHYDROFOLATESYNTH-RXN
|
|
|
|
6-hydroxymethyl-7,8-dihydropterin_diphosphate + 4-Aminobenzoic_acid <=> 7,8-dihydropteroate + diphosphate
|
2.5.1.15
dihydropteroate synthase
|
–
|
MK
|
| |
BRENDA:
BR47663
KEGG:
R03067
MetaCyc:
H2PTEROATESYNTH-RXN
SABIO-RK:
2910
|
|
|
|
2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + 4-Aminobenzoic_acid <=> 7,8-dihydropteroate + H2O
|
2.5.1
2.5.1.15
dihydropteroate synthase
|
–
–
|
K
|
| |
KEGG:
R03066
MetaCyc:
RXN-14226
|
|
|
|
GTP + 7,8-dihydropteroate + L-glutamate <=> GDP + phosphate + 7,8-dihydrofolate
|
6.3.2.12
dihydrofolate synthase
|
–
|
|
| |
BRENDA:
BS431
|
|
|
|
dATP + 7,8-dihydropteroate + L-glutamate <=> dADP + phosphate + 7,8-dihydrofolate
|
6.3.2.12
dihydrofolate synthase
|
–
|
|
| |
BRENDA:
BS428
|
|
|
|
7,8-dihydrofolate + H2O <=> 7,8-dihydropteroate + L-glutamate
|
3.4.17.11
glutamate carboxypeptidase
|
–
|
|
| |
BRENDA:
BS361735
|
|
|
|
ITP + 7,8-dihydropteroate + L-glutamate <=> IDP + phosphate + 7,8-dihydrofolate
|
6.3.2.12
dihydrofolate synthase
|
–
|
|
| |
BRENDA:
BS430
|
|
|
|
UTP + 7,8-dihydropteroate + L-glutamate <=> UDP + phosphate + 7,8-dihydrofolate
|
6.3.2.12
dihydrofolate synthase
|
–
|
|
| |
BRENDA:
BS429
|
|
|
|
7,8-dihydropteroate + NADH <=> tetrahydropteroate + NAD+
|
1.5.1.34
6,7-dihydropteridine reductase
|
–
|
|
| |
BRENDA:
BS319535-a
|
|
|
|
7,8-dihydropteroate + NADPH <=> tetrahydropteroate + NADP+
|
1.5.1.34
6,7-dihydropteridine reductase
|
–
|
|
| |
BRENDA:
BS319535
|
|
|
|
ATP + 7,8-dihydropteroate + L-glutamate <=> ADP + phosphate + folate
|
6.3.2.17
tetrahydrofolate synthase
|
–
|
|
| |
BRENDA:
BS400063
|
|
|
|
ATP + 7,8-dihydropteroate + L-glutamate <=> ADP + 7,8-dihydrofolate
|
6.3.2.17
tetrahydrofolate synthase
|
–
|
|
| |
BRENDA:
BS369060
|
|
|
|
2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + 4-Aminobenzoic_acid <=> 7,8-dihydropteroate + diphosphate
|
2.5.1.15
dihydropteroate synthase
|
–
|
|
| |
BRENDA:
BS378894
|
|
|
|
2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + ATP + 4-Aminobenzoic_acid <=> 7,8-dihydropteroate + diphosphate + AMP
|
2.7.6.3
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
|
–
|
|
| |
SABIO-RK:
15424
|
|
